John Wayne

Phyllis Fraser

Lew Kelly

Douglas Cosgrove

Lane Chandler

The arrival of the telegraph put Pony Express riders like John Blair and his pal Smoky out of work. A race will decide whether they or stageline owner Drake get the government mail contract.

A group of people traveling on a stagecoach find their journey complicated by the threat of Geronimo, and learn something about each other in the process.

A gang of bandits takes control of Tucson in preparation for the arrival of a consignment of gold, with only a band of voluntary soldiers trying to outwit them and save the town.

When Rocklin arrives in a western town he finds that the rancher who hired him as a foreman has been murdered. He is out to solve the murder and thwart the scheming to take the ranch from its rightful owner.

Eddie and his sidekicks have been called in to help get a new telegraph line through. Dawson and his men along with his stooge Judge are out to stop them. When Eddie and the boys catch three of Dawson's men destroying telegraph equipment, the Judge releases them and this leads to the showdown between the two sides.

Jesse W. Haywood (Don Knotts) graduates from dental school in Philadelphia in 1870 and goes west to become a frontier dentist. Penelope "Bad Penny" Cushing (Barbara Rhoades) is offered a pardon if she will track down a ring of gun smugglers. She tricks Haywood into a sham marriage as a disguise. Haywood inadvertently becomes the legendary "Doc the Haywood" after he guns down "Arnold the Kid".

Double-crossed and left without water in the desert, Cable Hogue is saved when he finds a spring. It is in just the right spot for a much needed rest stop on the local stagecoach line, and Hogue uses this to his advantage. He builds a house and makes money off the stagecoach passengers. Hildy, a prostitute from the nearest town, moves in with him. Hogue has everything going his way until the advent of the automobile ends the era of the stagecoach.

A stage headed West with a group of passengers is attacked by Cheyenne Indians, and takes refuge in a nearby ghost town.

In a rigged gunfight Tom Blake is forced to shoot a man in self defense and is then hunted for murder. After a long trip fleeing the posse he uses a false name and joins the Pony Express which is just about to commence operatons. Relegated to the most dangerous section of the route, he finds himself fighting the District Manager's scheme to sabotage the inital run. But just then a wanted poster with his picture on it arrives.