Johnny Mack Brown

Fuzzy Knight

William Farnum

Rex Lease

Helen Deverell

It is now an accepted fact that the best of Johnny Mack Brown's Universal westerns were directed by the talented Joseph H. Lewis. Boss of Hangtown Mesa may not be in the same league as the Brown-Lewis classic Arizona Cyclone, but it comes awfully close. This time around, hero Steve Collins (Brown) comes to the aid of Betty Wilkins (Helen Deverell), who has taken over the telegraph-line business established by her uncle John (Henry Hall). The latter was murdered by outlaws who don't cotton to having the territory linked up electronically with the rest of the world.

Marshall Jed Cooper survives a hanging, vowing revenge on the lynch mob that left him dangling. To carry out his oath for vengeance, he returns to his former job as a lawman. Before long, he's caught up with the nine men on his hit list and starts dispensing his own brand of Wild West justice.

Stodge City is in the grip of the Rumpo Kid and his gang. Mistaken identity again takes a hand as a 'sanitary engineer' named Marshal P. Knutt is mistaken for a law marshal. Being the conscientious sort, Marshal tries to help the town get rid of Rumpo, and a showdown is inevitable. Marshal has two aids—revenge-seeking Annie Oakley and his sanitary expertise.

Wealthy rancher Bick Benedict and dirt-poor cowboy Jett Rink both woo Leslie Lynnton, a beautiful young woman from Maryland who is new to Texas. She marries Benedict, but she is shocked by the racial bigotry of the White Texans against the local people of Mexican descent. Rink discovers oil on a small plot of land, and while he uses his vast, new wealth to buy all the land surrounding the Benedict ranch, the Benedict's disagreement over prejudice fuels conflict that runs across generations.

The arrival of the telegraph put Pony Express riders like John Blair and his pal Smoky out of work. A race will decide whether they or stageline owner Drake get the government mail contract.

Outlaw and self-appointed lawmaker Judge Roy Bean rules over an empty stretch of the West that gradually grows, under his iron fist, into a thriving town, while dispensing his his own quirky brand of frontier justice upon strangers passing by.

Two-fisted cowboys fight for law and order in their encounters with outlaws.

After arriving at his new, remote Army outpost, Capt. John Boyd and his regiment aid a wounded frontiersman who recounts a horrifying tale of a wagon train murdered by its supposed guide – a vicious U.S. Army colonel gone rogue. Fearing the worst, the regiment heads out into the wilderness to verify the gruesome claims.

Eddie and his sidekicks have been called in to help get a new telegraph line through. Dawson and his men along with his stooge Judge are out to stop them. When Eddie and the boys catch three of Dawson's men destroying telegraph equipment, the Judge releases them and this leads to the showdown between the two sides.